Cd84 gene function
WebCD84 is a 64-82 kD glycoprotein. It is a member of the SLAM (CD150) family, a CD2 subset of the Ig superfamily, also known as SLAMF5 or Ly9b. CD84 is expressed on B cells, monocytes, thymocytes, subset of T cells, and platelets. CD84 functions as a homophilic adhesion molecule and enhances T cell activation and cytokine production. WebCD84 is a member of the CD2 subset of the immunoglobulin superfamily of cell surface receptors. ... somatically mutated Ig variable region genes, and increased proliferation compared to CD84(lo) B cells. ... and its signal transduction pathway may utilize SAP and/or EAT-2. Thus, investigation of expression and function of CD84 and CD27 is ...
Cd84 gene function
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WebFeb 25, 2013 · CD84 expression is elevated in CLL cells in a MIF/CD74-dependent manner. To better understand the biological function of CD74 in CLL cells, we sought to identify target genes induced by CD74 ... WebFeb 22, 2024 · Its activation leads to an elevation of expression of genes regulating differentiation to monocytic/granulocytic-myeloid-derived suppressor cells (M-MDSCs …
WebOct 21, 2024 · SLAM family member 5, leukocyte differentiation antigen CD84, signaling lymphocytic activation molecule 5. GeneRIFs: Gene References Into Functions. CD84 is a Suppressor of T and B Cell Activation during Mycobacterium tuberculosis Pathogenesis. Circ-Usp10 promotes microglial activation and induces neuronal death by targeting … WebCD84. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC.
Web2 days ago · April 12, 2024. Credit: Alfred Pasieka / Getty Images / Science Photo Library. Precision medicine company Function Oncology has officially launched with the goal of revolutionizing the future of ... WebCD84 (SLAMF5) is a member of the SLAM family of cell-surface immunoreceptors. Broadly expressed on most immune cell subsets, CD84 functions as a homophilic adhesion …
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WebCD84. Status. UniProtKB reviewed (Swiss-Prot) Organism. Homo sapiens (Human) Amino acids. 345. ... B-cell contact, optimal T follicular helper function, and germinal center … good names for clownsWebCD84. Immunoglobulin superfamily domain containing, CD molecules (CD) This gene encodes a membrane glycoprotein that is a member of the signaling lymphocyte activation molecule (SLAM) family. This family forms a subset of the larger CD2 cell-surface receptor Ig superfamily. The encoded protein is a homophilic adhesion molecule that is expressed ... chester ca newsMembers of the CD2 (see MIM 186990) subgroup of the Ig superfamily, such as CD84, have similar patterns of conserved disulfide bonds and function in adhesion interactions between T lymphocytes and accessory cells. good names for cloudsWebJul 1, 2024 · CD84 is a single chain type-I glycoprotein of a molecular weight of 64 to 82 kDa. The CD84 ectodomain consists of a non-canonical membrane-distal V-Ig domain, which lacks the usually conserved disulphide bonds between β sheets, and one membrane-proximal C2-Ig domain (Fig. 1 A).The CD84 V-Ig domain is structured as a two-layer β … chester canal tripsWebCadherin-1 or Epithelial cadherin (E-cadherin), (not to be confused with the APC/C activator protein CDH1) is a protein that in humans is encoded by the CDH1 gene. Mutations are correlated with gastric, breast, colorectal, thyroid, and ovarian cancers.CDH1 has also been designated as CD324 (cluster of differentiation 324). It is a tumor suppressor gene. chester ca newspaper daily newsWebThe .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site. good names for clothing businessWebDec 28, 2016 · At 8 h following CD74 activation, both the up- and down-regulated genes had a significantly higher regulatory potential relative to the nonregulated genes (P = 3.98 × 10 −09 and P = 7.67 × 10 −07, respectively) (Fig. 3C), indicating that CD74 association with the chromatin directly affects gene transcription, and that CD74 functions both ... good names for clownfish