Cisplatin induced hyponatremia
WebThe possibility of Cisplatin induced renal salt wasting was considered. The patient was started on Fludrocortisone 0.1mg twice daily, oral salt tablets 1g QID, sodium bicarbonate tablets 650mg TID and normal saline at 150ml/h. ... PROFOUND HYPONATREMIA AND DEHYDRATION: A CASE OF CISPLATIN INDUCED SALT LOSING NEPHROPATHY. … WebFeb 16, 2024 · cycles of therapy (with cumulative cisplatin dose of Cancer therapy-induced hyponatremia: A case-illustrated review Karyne Pelletier, Marko Škrtić and Abhijat …
Cisplatin induced hyponatremia
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WebApr 12, 2024 · At the same time, hyponatremia should be related to brain and adrenal metastasis, paraneoplastic syndrome, ... In this case, the standard approach to avoid cisplatin-induced nephrotoxicity and the consequent electrolyte alteration is the administration of IV isotonic saline solution in order to stimulate the diuresis. Some … WebThe mainstay approach to prevent cisplatin-induced nephrotoxicity is administering intravenous (IV) hydration with isotonic saline to increase renal blood flow, and decline in half-life of cisplatin and urinary cisplatin concentration. 5 Additionally, many other agents have been studied, such as mannitol, N-acetylcysteine, and furosemide ...
WebHyponatremia after chemotherapy is not an uncommon clinical syndrome. Both renal salt-wasting syndrome (RSWS) and syndrome of inappropriate antidiuretic hormone … WebBoth renal salt-wasting syndrome (RSWS) and syndrome of inappropriate antidiuretic hormone secretion (SIADH) have been reported as the underlying mechanisms for chemotherapy-induced hyponatremia. However, these two clinical syndromes have distinct clinical characteristics and managements.
WebWe report a rare case of severe hyponatremia due to cisplatin-induced syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in a 74-year-old male with a … WebNational Center for Biotechnology Information
WebCDDP-induced hyponatremia has also occurred in a case of renal salt-wasting syndrome, 4 in patients with nausea/vomiting/anorexia, and when vigorous hydration was …
WebJul 8, 2010 · Cisplatin based therapy for the treatment of solid organ tumors is commonly associated with several renal abnormalities including; *hypokalemia. * hypomagnesemia. … china star cheshuntWebAug 1, 2002 · We report a case of a patient with hyponatremia and excessive urinary excretion of sodium after cisplatin-based chemotherapy. RSWS was diagnosed and the patient was treated with a sodium supplement. We also summarize the key diagnostic features and the most common differential diagnoses for hyponatremia syndrome. china star covington gaWebJan 1, 2024 · Univariable analysis revealed a high incidence of hyponatremia in patients receiving cisplatin, three-drug combination regimen, two-drug combination regimen with amrubicin or irinotecan, or high-dose cisplatin (weekly equivalent cisplatin dose ≥20 mg/m2), and in patients with small-cell lung cancer. Conclusion grammy foundationWebHyponatremia due to syndrome of inappropriate antidiuretic hormone secretion (SIADH) or gastrointestinal loss of sodium is sometimes seen during chemotherapy. However, … china star coventryWebDec 16, 2024 · Cisplatin induces acute ischemic injury, resulting in decreased renal medullary blood flow ( 24) and renal tubular cell damage ( 25 ). Meanwhile, cisplatin can block calcium ion channels to reduce COX-2 and prostaglandin, cause vasoconstriction, and eventually lead to aggravation of hypoxia ( 26 ). china star coral springs flWebHyponatremia after chemotherapy is not an uncommon clinical syndrome. Both renal salt-wasting syndrome (RSWS) and syndrome of inappropriate antidiuretic hormone secretion (SIADH) have been reported as the underlying mechanisms for chemotherapy-induced hyponatremia.However, these two clinical syndromes have distinct clinical … china star county line road spring hill flWebAbstract We report a rare case of cisplatin-induced acute hyponatremia leading to a seizure and coma. A 66-year-old woman with breast cancer received adjuvant chemotherapy with docetaxel and cisplatin. She had no nausea, vomiting, or diarrhea during or after chemotherapy administration. grammy for prince ha