Cullin family protein binding
WebOct 13, 2024 · Gene ID: 54638, updated on 13-Oct-2024 Summary Predicted to enable cullin family protein binding activity. Predicted to be involved in several processes, including cytoplasmic sequestering of NF-kappaB; regulation of I-kappaB kinase/NF-kappaB signaling; and vesicle-mediated transport to the plasma membrane. WebApr 12, 2024 · This variant Spry2 behavior, linked to specific stimuli or cell types, seems to depend on its binding to protein phosphatase 2 A (PP2A) and the resulting dephosphorylation of certain residues of ...
Cullin family protein binding
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Webprotein binding cullin family protein binding (GO:0097602) is_a protein binding dynein heavy chain binding (GO:0045504) is_a protein binding modification-dependent protein binding (GO:0140030) is_a protein binding growth factor binding (GO:0019838) is_a protein binding WebApr 12, 2024 · The damaged DNA-binding protein 1 (DDB1) enhances the survival and maintenance of multipotent cells through promoting the Cullin 4 E3 ligase complex-dependent ubiquitination and subsequent degradation of downstream substrates. Naive T cells could be activated and differentiated into effector and memory T cells by exogenous …
http://amigo.geneontology.org/amigo/term/GO:0097602 http://amigo.geneontology.org/amigo/term/GO:0005515
WebCullin-4A is a protein that in humans is encoded by the CUL4A gene. CUL4A belongs to the cullin family of ubiquitin ligase proteins and is highly homologous to the CUL4B protein. CUL4A regulates numerous key processes such as DNA repair, chromatin remodeling, spermatogenesis, haematopoiesis and the mitotic cell cycle.As a result, … WebCullin 1, also known as CUL1, is a human protein and gene from cullin family. This protein plays an important role in protein degradation and protein ubiquitination .
WebAug 14, 2001 · The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (PubMed:12609982, PubMed:24076655, PubMed:27565346).
WebJun 22, 2007 · CUL3 CRLs use B ric-a-brac, T ramtrack, and B road (BTB) domain-containing proteins that integrate the functions of both adaptor and substrate receptors. A common structural feature shared among the cullin adaptors is the BTB fold, which consists of five α helices separated by three antiparallel β strands. greens astro shower mixerWebMar 21, 2024 · Summary Enables cullin family protein binding activity. Involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; regulation of protein neddylation; and response to UV-C. Located in nucleus; perinuclear region of cytoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2024] greens at arboretum pinehurstWebNov 28, 2024 · Recently, a novel ubiquitin-binding domain was identified at the C-terminal end of KHNYN (also called KIAA0323) protein. This domain, called CUBAN for cullin binding domain associating with NEDD8, shows a clear preference for monomeric NEDD8 and mediates the interaction of KHNYN with neddylated cullins [10,11]. Although the … fm 199 inspired byWebDec 4, 2011 · Cullin proteins are molecular scaffolds that have crucial roles in the post-translational modification of cellular proteins involving ubiquitin. The mammalian cullin … greens at cannondale wiltonWebThe evolutionarily conserved cullin family proteins can assemble as many as 400 distinct E3 ubiquitin ligase complexes that regulate diverse cellular pathways. CUL4, one of three founding cullins conserved from yeast to humans, uses a large beta-propeller protein, DDB1, as a linker to interact with … CRL4s: the CUL4-RING E3 ubiquitin ligases greens at auburnWebMar 21, 2024 · Enables cullin family protein binding activity. Involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; regulation of protein neddylation; and response to UV-C. Located in nucleus; perinuclear region of cytoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2024] greens at chapel creek shawneeWebMar 21, 2024 · Enables cullin family protein binding activity. Involved in positive regulation of protein neddylation. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2024] GeneCards Summary for DCUN1D2 Gene DCUN1D2 (Defective In Cullin Neddylation 1 Domain Containing 2) is a Protein Coding gene. greens at chestnut ridge apartments