Palmitoyl-protein thioesterase 1 ppt1
WebThe synthetic substrate for palmitoyl-protein thioesterase 1 (PPT1) is 4-methylumbelliferyl-6-thiopalmitoyl-beta-glucoside. The leukocytes are homogenized and combined with … WebBiological Activity. GNS561 (Ezurpimtrostat, GNS-561) is a novel lysosomotropic agent and autophagy inhibitor that induces lysosomal cell death, targets palmitoyl-protein …
Palmitoyl-protein thioesterase 1 ppt1
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WebPalmitoyl protein hydrolase/thioesterases is an enzyme (EC 3.1.2.22) that removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in … WebMar 13, 2024 · Palmitoyl-protein thioesterase 1 (PPT1) is a depalmitoylation enzyme that is mutated in cases of neuronal ceroid lipofuscinosis (NCL). The hallmarks of the disease …
WebMar 31, 2024 · Unbiased proteomics with acyl resin-assisted capture reveals diverse novel substrates of the depalmitoylating enzyme palmitoyl protein thioesterase 1 (PPT1) at the … WebFor example, low activity of the enzyme palmitoyl-protein thioesterase-1 (PPT1) contributes to the infantile form of Batten disease (now referred to as CLN1). In the late infantile form …
WebNov 22, 2024 · UniProtKB unreviewed (TrEMBL) Organism. Homo sapiens (Human) Amino acids. 78. Protein existence. Evidence at protein level. Annotation score. 1/5. WebPalmitoyl-protein thioesterase 1 (PPT1) is a depalmitoylation enzyme that is mutated in cases of neuronal ceroid lipofuscinosis (NCL). The hallmarks of the disease include progressive neurodegeneration and blindness, as well as seizures. In the current study, we identified 62 high-confident PPT1-binding proteins. These proteins included a self …
WebK01074 PPT; palmitoyl-protein thioesterase 09140 Cellular Processes 09141 Transport and catabolism 04142 Lysosome K01074 PPT; palmitoyl-protein thioesterase 09180 ... MS3_00002529(PPT1_1) MS3_00010296(PPT1_5) OVI: T265_08176: EGL: EGR_01013: NVE: 5502636 5511348: EPA: 110234994 110246285: ATEN: 116290473 116291267 …
WebOne of the upregulated spots was palmitoyl-protein thioesterase 1 (PPT1), a lipoprotein metabolizing related enzyme localized to Sertoli cells. In a Sertoli-cell line cultured in a … christian termsWebMay 28, 2024 · e16175 Background: GNS561 belongs to a novel generation of drug blocking cancer cell proliferation by inhibiting late-stage autophagy and dose-dependent … christian terms dictionaryWebMar 21, 2024 · PPT1 (Palmitoyl-Protein Thioesterase 1) is a Protein Coding gene. Diseases associated with PPT1 include Ceroid Lipofuscinosis, Neuronal, 1 and Neuronal Ceroid … geotechnical engineering universityWeb产品名称:PPT1 Antibody, Biotin conjugated产品货号:CSB-PA018587LD01HU产品别名:Ceroid palmitoyl palmitoyl protein thioesterase 1 antibody; CLN1 antibody; E geotechnical engineering webinarsWebMay 27, 2024 · In this study, we focused on the expression and function of palmitoyl protein thioesterase 1 (PPT1), a lysosomal depalmitoylating enzyme, in Sertoli cells. Here, we … christian terms glossaryWebNX_P50897 - PPT1 - Palmitoyl-protein thioesterase 1 - Function. Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or … geotechnical engineering winnipegWebFeb 15, 2024 · Palmitoyl-protein thioesterase 1 ( Ppt1) encodes a lysosomal enzyme that removes palmitoyl groups from particular target proteins during protein degradation … christian terms and definitions